Sono solo due le teste di serie del tabellone maschile eliminate nel primo giorno degli US Open, ma una di queste piuttosto importante. Giunto fino ai quarti di finale un anno fa, il numero 13 del tabellone a Flushing Meadows Richard Gasquet (ATP 15) si è arreso al 21enne britannico Kyle Edmund (84) con il netto punteggio di 6-2 6-2 6-3. Anche il numero 28 del seeding Martin Klizan (29) è già stato costretto a fare i bagagli dopo la sconfitta per 6-2 6-1 6-1 con il veterano Mikhail Youzhny (61).
Se la sono vista brutta gli americani John Isner (21), vittorioso al tie-break del quinto nel derby con il 18enne Frances Tiafoe (125), che ha pure servito per il match sul 5-3, e Jack Sock (27), impostosi sempre nel set decisivo per 6-4 sull'altro giovane connazionale Taylor Fritz (53).
Hanno dal canto loro avuto un'entrata in materia non troppo impegnativa Novak Djokovic (1) e Rafael Nadal (5). Il serbo ha concesso un set al polacco Jerzy Janowicz (247), ma ha dominato negli altri chiudendo con il risultato di 6-3 5-7 6-2 6-1, mentre lo spagnolo ha liquidato l'uzbeko Denis Istomin (107) per 6-1 6-4 6-2. Avanti in tre parziali pure Milos Raonic (6), il campione del 2014 Marin Cilic (9), Jo-Wilfried Tsonga (11) e Gael Monfils (12).
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