L'Uruguay, una delle grandi favorite per la vittoria della Copa America insieme a Brasile ed Argentina, non ha fallito l'esordio nella competizione, sconfiggendo senza troppi problemi l'Ecuador per 4-0. A Belo Horizonte la Celeste ha archiviato la pratica già nel primo tempo, grazie anche ad un'espulsione severa ai danni dell'ecuadoriano Quinteros. Lodeiro, Cavani e Suarez hanno indirizzato la gara, chiusa definitivamente da un autogol di Mina nei secondi 45'.
Nell'altra partita disputata il Qatar ha pareggiato in rimonta con il Paraguay per 2-2 al Maracanã di Rio de Janeiro. I sudamericani, passati in doppio vantaggio con Cardozo e Gonzalez, si sono fatti recuperare dagli asiatici che hanno trovato il gol con Almoez e Khoukhi.
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