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È possibile risvegliare il virus HIV latente grazie ad una molecola che viene già usata in alcuni farmaci anti-tumorali. La scoperta, che potrebbe aprire la strada verso la completa eradicazione del virus dell'Aids dall'organismo, viene annunciata sulla rivista Plos Pathogens dai ricercatori dell'Università della California a Davis, nei dintorni di Sacramento.
La molecola che dà la sveglia al virus dell'immunodeficienza umana HIV si chiama ingenolo mebutato (PEP005) e nei test, condotti su campioni di sangue estratto da pazienti, ha dimostrato di favorire la riattivazione del virus comportando una ridotta tossicità.
Questo risultato è molto importante, perché risvegliare il virus significa renderlo nuovamente visibile ai “radar” delle difese immunitarie e dei farmaci antiretrovirali. Si tratta del primo passo per puntare alla completa guarigione dall'infezione.
ANSA/SP
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